PA1-22498 detects Lymphotactin in Rat samples.
Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.
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Protein Aliases: C motif chemokine 1; Cytokine SCM-1; Lymphotactin; SCM-1-beta; SCM-1alpha; SCM-1beta; SCM1alpha; SCM1beta; small inducible cytokine subfamily C, member 1 (lymphotactin); Small-inducible cytokine C1
Gene Aliases: Ltn; Scyc1; Xcl1
UniProt ID: (Rat) P51672
Entrez Gene ID: (Rat) 171371