CDH15 is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. This protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
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Protein Aliases: Cadherin-14; Cadherin-15; CDH14; CDH15; CDH3; M cadherin; M-cadherin; Muscle cadherin
Gene Aliases: AI323380; Cdh14; Cdh15; Mcad
UniProt ID: (Mouse) P33146
Entrez Gene ID: (Mouse) 12555
Molecular Function: cadherin