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Invitrogen
CD2/CD20 Antibody Cocktail, FITC, PE
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Product Details
MA1-12059
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1/IgG2a
Class
Cocktail
Type
Antibody
Clone
T6.3, DFA-7
Immunogen
T lymphocytes activated by mixed lymphocyte culture and the LB lymphoblastoid cell line
Conjugate
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is a monoclonal mixture of FITC-conjugated CD2 (clone T6.3, isotype IgG2a) and PE-conjugated CD20 (clone DFA-7, isotype IgG1).
Target Information
CD2 is found on the majority of human T and NK cells. CD2 presents on 78+8% normal peripheral lymphocytes and 100% of thymocytes. This antibody detects CD2 antigen CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2CD2 antigen; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 surface antigen; CD20; CD20 antigen; CD20 receptor; Erythrocyte receptor; Leukocyte surface antigen Leu-16; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; Membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; MGC3969; Rosette receptor; surface antigen CD2 precursor; T-cell surface antigen CD2; T-cell surface antigen CD2 precursor; T-cell surface antigen T11/Leu-5; unnamed protein product
Gene Aliases: B1; Bp35; CD2; CD20; CVID5; FMC7; LEU-16; LFA-2; MS4A1; S7; SRBC; T11
UniProt ID: (Human) P06729, (Human) P11836
Entrez Gene ID: (Human) 914, (Human) 931
store-operated calcium entry
humoral immune response
cell surface receptor signaling pathway
response to bacterium
B cell differentiation
B cell proliferation
B cell activation
B cell receptor signaling pathway
protein tetramerization
calcium ion import into cytosol
positive regulation of calcium ion import across plasma membrane
membrane raft polarization
apoptotic process
immune response
cell adhesion
natural killer cell activation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
heterotypic cell-cell adhesion
T cell activation
natural killer cell mediated cytotoxicity
regulation of T cell differentiation
cell-cell adhesion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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