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Invitrogen
CD9 Monoclonal Antibody (MM2/57)
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FIGURE: 1 / 5
CD9 Antibody (MA1-80307) in WB
Molecules (Basel, Switzerland) 2022 -
Characterization of exosome fractions concentrated from serum. ( a ) Dynamic light scattering measurements. Size and zeta potential distribution (10 measurements, each) for samples concentrated from pregnant women without (CG) and with diabetes (GDM). ( b ) Detection of exosome markers CD9 and CD63 by Western blot in serum exosome fractions concentrated from CG and GDM. ( c ) Principal component analysis pl... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-80307
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Cat,
Human,
Mink,
Pig,
Rabbit,
Rhesus monkey
Published species
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
MM2/57
Immunogen
Human platelet membrane.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with mustelid based on sequence homology.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Human CD9 antibody, clone MM2/57 recognizes human leukocyte antigen MIC3 also known as MRP-1 or CD9.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; BTCC-1p; CD9 antigen; CD9 antigen (p24); cell growth-inhibiting gene 2 protein; GIG2; leukocyte antigen MIC3; mamu-MICA/B; MHC class I polypeptide-related sequence 3; MHC class I-related chain; motility related protein-1; sCD 9; sCD9; soluble CD 9; soluble CD9; tetraspanin-29; Tetraspanin29; unnamed protein product
Gene Aliases: BTCC-1; DRAP-27; Mamu-MIC1; MIC3; MRP-1; TSPAN-29; TSPAN29
UniProt ID: (Pig) Q8WMQ3, (Bovine) P30932, (Human) P21926, (Cat) P40239
cell adhesion
single fertilization
fusion of sperm to egg plasma membrane
myoblast fusion involved in skeletal muscle regeneration
paranodal junction assembly
receptor internalization
sperm-egg recognition
negative regulation of cellular component movement
cellular response to low-density lipoprotein particle stimulus
negative regulation of platelet aggregation
negative regulation of cell proliferation
glial cell migration
regulation of macrophage migration
nervous system development
oligodendrocyte development
cell differentiation
platelet activation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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