Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
MA5-14273 targets p130Cas in IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.
The MA5-14273 immunogen is recombinant human p130Cas protein.
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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