This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MA5-14435 targets Vimentin in IHC (P) applications and shows reactivity with Human samples.
The MA5-14435 immunogen is vimentin - recombinant protein encoding human Vimentin, gp100 - Extract of pigmented melanoma metastases from lymph nodes.
Host/Isotype: Rabbit/Mouse / IgG/IgG1, kappa
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis luminal protein 113; FLJ36605; VIM; Vimentin
Gene Aliases: CTRCT30; HEL113; VIM
UniProt ID: (Human) P08670
Entrez Gene ID: (Human) 7431