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Invitrogen
CD52 Monoclonal Antibody (YTH34.5)
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Product Details
MA5-16999
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rhesus monkey
Published species
Human
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
YTH34.5
Immunogen
human lymphocytes
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
500 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is a low-endotoxin, preservative-free formulation.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. A suggested positive control for immunohistochemical applications is tonsil. For cytotoxic assays, use human serum as a complement source.
Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cambridge pathology 1 antigen; CAMPATH-1 antigen precursor; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDW52; CDW52 antigen (CAMPATH-1 antigen); epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; HEL-S-171mP; human epididymis-specific protein 5
Gene Aliases: CDW52; EDDM5; EGK_00417; HE5
UniProt ID: (Human) P31358
Entrez Gene ID: (Human) 1043, (Rhesus monkey) 714429
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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