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          • Primary Antibodies ›
          • MHC Class I (H-2Db) Antibodies

          Invitrogen

          H-2Db Monoclonal Antibody (B22-249.R1)

          3 References
          View all (27) MHC Class I (H-2Db) antibodies

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          Cite H-2Db Monoclonal Antibody (B22-249.R1)

          Additional Information:
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          Product Details

          MA5-17992

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          Assay-dependent
          View 3 publications 3 publications

          Cytotoxicity Assay (Cytotoxicity)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Mouse

          Published species

          Mouse

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          B22-249.R1

          Immunogen

          Mouse H-2Db

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • FITC
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          250 µg

          Purification

          Protein G

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2539376

          Product Specific Information

          MA5-17992 targets H-2Db in CT applications and shows reactivity with Mouse samples.

          The MA5-17992 immunogen is mouse H-2Db.

          Target Information

          This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8.

          HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: H-2 class I histocompatibility antigen, D-B alpha chain; H-2D cell surface glycoprotein; H-2D(B); H2-DC1-beta transplantation antigen protein; H2D1; H2DB; H2L; H2LD; MHC class I antigen; MHC class I H-2Dp; MHC class I H2 antigen; MHC H2-D-q alpha-chain; Q5k protein

          View more View less

          Gene Aliases: H-2D; H2-D; H2-D1

          View more View less

          UniProt ID: (Mouse) P01899

          View more View less

          Entrez Gene ID: (Mouse) 14964

          View more View less

          Function(s)
          receptor binding protein binding beta-2-microglobulin binding peptide binding peptide antigen binding T cell receptor binding poly(A) RNA binding TAP binding protein heterodimerization activity major histocompatibility complex protein
          Process(es)
          positive regulation of T cell mediated cytotoxicity immune system process antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent immune response antigen processing and presentation
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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