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Invitrogen
H-2Ld Monoclonal Antibody (30-5-7S), FITC
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Product Details
MA5-18006
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
30-5-7S
Immunogen
mouse H-2Ld (public determinant H-2.65)
Conjugate
FITC
FITC
FITC
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 4-5mg/mL BSA
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-18006 targets H-2Ld in CT and FACS applications and shows reactivity with Mouse samples.
The MA5-18006 immunogen is mouse H-2Ld (public determinant H-2.65).
Target Information
MHC Class I (H-2Ld) is a protein complex located on the surface of cells in vertebrates. Its main function is to present peptides derived from intracellular proteins to T cells for immune recognition. The structure of MHC Class I (H-2Ld) consists of a heavy chain, beta-2 microglobulin, and a peptide-binding groove that interacts with antigenic peptides. The location of MHC Class I (H-2Ld) varies depending on the cell type, but it is typically found on the surface of nucleated cells.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h-2d antigen; H-2L; H2L; H2LD; histocompatibility 2, L region
Gene Aliases: H-2L
Entrez Gene ID: (Mouse) 14980
receptor binding
beta-2-microglobulin binding
MHC class I protein binding
peptide antigen binding
T cell receptor binding
CD8 receptor binding
identical protein binding
protein homodimerization activity
natural killer cell lectin-like receptor binding
TAP binding
TAP1 binding
TAP2 binding
receptor agonist activity
chaperone binding
TAP complex binding
14-3-3 protein binding
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
defense response
immune response
signal transduction
antigen processing and presentation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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