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Invitrogen

CD112 (Nectin-2) Monoclonal Antibody (R2.525), PE

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CD112 (Nectin-2) Monoclonal Antibody (R2.525), PE

Product Details

MA5-28595

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

10 µL/1x10^6 cells
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

R2.525

Immunogen

Human Nectin-2- transfected NIH/3T3 cells
View immunogen

Conjugate

PE PE PE

Excitation/Emission Max

565/576 nm View spectra spectra

Form

Liquid

Purification

Size-exclusion chromatography

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

15mM sodium azide

Storage conditions

4°C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745554

Product Specific Information

This antibody recognizes an extracellular epitope on CD112, a type I transmembrane glycoprotein expressed by myelomonocytic and megakaryocytic cells, and by CD34+ hematopoietic progenitors.

Target Information

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

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Bioinformatics

Protein Aliases: CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; HveB; Nectin cell adhesion molecule 2; Nectin-2; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); Poliovirus receptor-related protein 2; PVRL2; unnamed protein product

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Gene Aliases: CD112; HVEB; NECTIN2; PRR2; PVRL2; PVRR2

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UniProt ID: (Human) Q92692

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Entrez Gene ID: (Human) 5819

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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