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Invitrogen

Neuroligin 1 Recombinant Rabbit Monoclonal Antibody (079)

View all (36) Neuroligin 1 antibodies

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Neuroligin 1 Recombinant Rabbit Monoclonal Antibody (079)

Product Details

MA5-29444

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

079

Immunogen

Recombinant Human Neuroligin 1/NLGN1 protein (Met1-Ser677)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2785306

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This antibody has specificity for Human Neuroligin 1/NLGN1.

Target Information

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC45115; Neuroligin-1; NLG 1; unnamed protein product

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Gene Aliases: KIAA1070; NL1; NLG1; NLGN1

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UniProt ID: (Human) Q8N2Q7

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Entrez Gene ID: (Human) 22871

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Function(s)
beta-amyloid binding PDZ domain binding signaling receptor activity neurexin family protein binding identical protein binding cell adhesion molecule binding scaffold protein binding
Process(es)
protein targeting cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules neuron cell-cell adhesion nervous system development synapse assembly positive regulation of circadian sleep/wake cycle, wakefulness synaptic vesicle targeting calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules neuronal signal transduction neuron projection development positive regulation of synaptic transmission, GABAergic protein localization to synapse establishment of protein localization regulation of neuron differentiation rhythmic process cytoskeletal matrix organization at active zone neuron projection morphogenesis modulation of synaptic transmission positive regulation of filopodium assembly positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis cellular response to calcium ion terminal button organization synaptic vesicle clustering postsynaptic membrane assembly presynaptic membrane assembly AMPA glutamate receptor clustering NMDA glutamate receptor clustering neurexin clustering involved in presynaptic membrane assembly postsynaptic density protein 95 clustering receptor localization to synapse NMDA selective glutamate receptor signaling pathway AMPA selective glutamate receptor signaling pathway presynapse assembly neuron projection arborization positive regulation of ruffle assembly positive regulation of neuromuscular synaptic transmission positive regulation of synaptic vesicle endocytosis positive regulation of intracellular signal transduction excitatory synapse assembly positive regulation of synaptic vesicle exocytosis positive regulation of excitatory postsynaptic potential
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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