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          • Primary Antibodies ›
          • OSMR Antibodies

          Invitrogen

          OSMR Recombinant Rabbit Monoclonal Antibody (002), APC

          1 Reference
          View all (22) OSMR antibodies

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          Cite OSMR Recombinant Rabbit Monoclonal Antibody (002), APC

          Additional Information:
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          • Antibody Testing Data (1)
          OSMR Antibody in Flow Cytometry (Flow)
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          OSMR Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          OSMR Antibody (MA5-46728) in Flow

          Flow cytometry analysis of OSMR in HeLa cells using OSMR, APC Recombinant Monoclonal (Product # MA5-46728). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          OSMR Antibody in Flow Cytometry (Flow)
          OSMR Recombinant Rabbit Monoclonal Antibody (002), APC

          Product Details

          MA5-46728

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          10 µL/test
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          002

          Immunogen

          Recombinant protein ecoding Human OSMR (Met1-Met740).
          View immunogen

          Conjugate

          APC APC APC
          • Unconjugated
          • PE 
          • Request custom conjugation

          Excitation/Emission Max

          651/660 nm View spectra spectra

          Form

          Liquid

          Concentration

          100 µg/mL

          Purification

          Protein A

          Storage buffer

          PBS with 0.5% BSA

          Contains

          0.03% ProClin 300

          Storage conditions

          4°C, store in dark, DO NOT FREEZE!

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2937800

          Product Specific Information

          Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR (Met1-Met740) and conjugated with APC under optimum conditions, the unreacted APC was removed.

          Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

          Target Information

          Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          How to use the Panel Builder

          Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

          Bioinformatics

          Protein Aliases: IL-31 receptor subunit beta; IL-31R subunit beta; Interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin-M specific receptor beta subunit; Oncostatin-M-specific receptor subunit beta; unnamed protein product

          View more View less

          Gene Aliases: IL-31R-beta; IL-31RB; OSMR; OSMRB; OSMRbeta; PLCA1

          View more View less

          UniProt ID: (Human) Q99650

          View more View less

          Entrez Gene ID: (Human) 9180

          View more View less

          Function(s)
          cytokine receptor activity oncostatin-M receptor activity ciliary neurotrophic factor receptor binding protein binding growth factor binding cytokine binding
          Process(es)
          positive regulation of acute inflammatory response positive regulation of cell proliferation cytokine-mediated signaling pathway response to cytokine oncostatin-M-mediated signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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