Sequence of this protein is as follows: MSSEQKSQHC KPEEGVEAQE EALGLVGAQA PTTEEQEAAV SSSSPLVPGT LEEVPAAESA GPPQSPQGAS ALPTTISFTC WRQPNEGSSS QEEEGPSTSP DAESLFREAL SNKVDELAHF LLRKYRAKEL VTKAEMLERV IKNYKRCFPV IFGKASESLK MIFGIDVKEV DPTSNTYTLV TCLGLSYDGL LGNNQIFPKT GLLIIVLGTI AMEGDSASEE EIWEELGVMG VYDGREHTVY GEPRKLLTQD WVQENYLEYR QVPGSNPARY EFLWGPRALA ETSYVKVLEH VVRVNARVRI AYPSLREAAL LEEEEGV
MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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Protein Aliases: Cancer/testis antigen 1.4; cancer/testis antigen family 1, member 4; CT1.4; MAGE-4 antigen; MAGE-41 antigen; MAGE-X2 antigen; melanoma antigen family A, 4; melanoma antigen family A4; Melanoma-associated antigen 4; MGC21336
Gene Aliases: CT1.4; MAGE-41; Mage-a4; MAGE-X2; MAGE4; MAGE4A; MAGE4B; MAGEA4
UniProt ID: (Human) P43358
Molecular Function: cell adhesion molecule