Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MLQTPESRG LPVPQAEGEK DGGHDGETRA PTASQERPKE ELGAGREEGA AEPALTRKGA RALAAKSLAR RRAYRRLNRT VAELVQFLLV KDKKKSPITR SEMVKYVIGD LKILFPDIIA RAAEHLRYVF GFELKQFDRK HHTYILINKL KPLEEEEEEE DLGGDGPRLG LLMMILGLIY MRGNSAREAQ VWEMLRRLGV QPSKYHFLFG YPKRLIMEDF VQQRYLSYRR VPHTNPPAYE FSWGPRSNLE ISKMEVLGFV AKLHKKEPQH WPVQYREALA DEADRARAKA RAEASMRARA SARAGIHLW (1-308 aa encoded by BC010056 )
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MAGE-F1; MAGE-F1 antigen; MAGF1; melanoma antigen family F, 1; melanoma antigen family F1; Melanoma-associated antigen F1; MGC19617
Gene Aliases: MAGEF1
UniProt ID: (Human) Q9HAY2
Entrez Gene ID: (Human) 64110
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