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Proteintech

MALT1 Polyclonal Antibody

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View all (42) MALT1 antibodies

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MALT1 Polyclonal Antibody

Product Details

11660-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 3 publications 3 publications

Immunohistochemistry (IHC)

-
View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:10-1:100
View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-

Immunoprecipitation (IP)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MALT1 Fusion Protein Ag2182 (125-450 aa encoded by BC030143)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PGIKITVNP ESKAVLAGQF VKLCCRATGH PFVQYQWFKM NKEIPNGNTS ELIFNAVHVK DAGFYVCRVN NNFTFEFSQW SQLDVCDIPE SFQRSVDGVS ESKLQICVEP TSQKLMPGST LVLQCVAVGS PIPHYQWFKN ELPLTHETKK LYMVPYVDLE HQGTYWCHVY NDRDSQDSKK VEIIIDELNN LGHPDNKEQT TDQPLAKDKV ALLIGNMNYR EHPKLKAPLV DVYELTNLLR QLDFKVVSLL DLTEYEMRNA VDEFLLLLDK GVYGLLYYAG HGYENFGNSF MVPVDAPNPY RSENCLCVQN ILKLMQEKET GLNVFLL (125-450 aa encoded by BC030143 )

Target Information

MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; malt1; MALT1 paracaspase; MALT1 protease; MALT1; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase; paracaspase-1; unnamed protein product

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Gene Aliases: A630046N12; D430033E09Rik; IMD12; MALT1; MLT; MLT1; PCASP1

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UniProt ID: (Human) Q9UDY8, (Mouse) Q2TBA3

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Entrez Gene ID: (Human) 10892, (Rat) 307366, (Mouse) 240354

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Function(s)
protease binding endopeptidase activity cysteine-type endopeptidase activity ubiquitin-protein transferase activity protein binding peptidase activity hydrolase activity kinase activator activity small molecule binding identical protein binding endopeptidase activator activity molecular_function signal transducer activity protein self-association cysteine protease
Process(es)
B-1 B cell differentiation immune system process positive regulation of immune effector process positive regulation of T cell cytokine production positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains proteolysis defense response response to fungus regulation of signal transduction positive regulation of protein ubiquitination lipopolysaccharide-mediated signaling pathway positive regulation of interleukin-1 beta production positive regulation of interleukin-2 production T cell proliferation B cell activation regulation of apoptotic process negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response T cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation nuclear export positive regulation of multicellular organismal process proteolysis involved in cellular protein catabolic process cellular response to lipopolysaccharide positive regulation of T-helper 17 cell differentiation response to molecule of bacterial origin activation of NF-kappaB-inducing kinase activity biological_process protein ubiquitination positive regulation of NF-kappaB transcription factor activity protein oligomerization apoptotic process I-kappaB kinase/NF-kappaB signaling
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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