PA5-28107 targets MAML1 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-28107 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human MAML1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mam-1; Mam1; MAML1; mastermind homolog; mastermind-like 1; Mastermind-like protein 1; mastermind-like transcriptional coactivator 1
Gene Aliases: AI644666; AW743257; D930008C07Rik; KIAA0200; Mam-1; Mam1; MAML1; mKIAA0200
Molecular Function: transcription factor