Immunogen sequence: YQVSQQQRQD QHSVVGQNTG PSPSPNPCSN PNTGSGYMNS QQSLLNQQLM GKKQTLQRQI MEQKQQLLLQ QQMLADAEKI APQDQINR
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KIAA1819; Mam-2; MAML2; mastermind-like 2; Mastermind-like protein 2; mastermind-like transcriptional coactivator 2
Gene Aliases: KIAA1819; MAM-3; MAM2; MAM3; MAML2; MLL-MAML2
UniProt ID: (Human) A7MD26
Entrez Gene ID: (Human) 84441
Molecular Function: transcription factor