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PA1-20468 detects G Protein-Coupled Receptor MRG in Human samples.
The proto-oncogene MAS1 is a G protein-coupled receptor located on the plasma membrane. In transfected NIH/3T3 cells, MAS1 has a weak focus-inducing activity. MAS1 is an antagonist of the AT1 receptor (Angiotensin II type 1 receptor), inhibiting the actions of Angiotensin II. MAS1L (MAS1-like), also known as MAS-L or MRG (Mas-related G-protein coupled receptor MRG), is a 378 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 (GPCR) family. MAS1 related proteins are thought to regulate nociceptor function and development, including the sensation or modulation of pain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAAP-341G9.4; MAS-R; mas-related G protein-coupled MRG; Mas-related G-protein coupled receptor MRG; MAS1 oncogene-like; MAS1-like; MGC119987; Mrg and gpcr
Gene Aliases: dJ994E9.2; MAS-L; MAS1L; MRG
UniProt ID: (Human) P35410
Entrez Gene ID: (Human) 116511
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