Product References
ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis.
The Journal of experimental medicine
Moguche AO,Shafiani S,Clemons C,Larson RP,Dinh C,Higdon LE,Cambier CJ,Sissons JR,Gallegos AM,Fink PJ,Urdahl KB
MCD0400 was used in flow cytometry to assess a CD 4 T-cell population during tuberculosis that has memory-like properties maintained by Bcl6 and ICOS-dependent pathways
Mon May 04 00:00:00 EDT 2015
Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells.
PloS one
Fontinha D,Lopes FB,Marques S,Alenquer M,Simas JP
MCD0400 was used in flow cytometry to determine the promotion of the formation of conjugates between transformed T helper cells and B lymphoma cells by murid gammaherpesvirus latency-associated protein M2
Thu Jun 23 00:00:00 EDT 2016
Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function.
PloS one
Gardner JK,Mamotte CD,Patel P,Yeoh TL,Jackaman C,Nelson DJ
MCD0400 was used in flow cytometry to characterize dendritic cell lipid content, function and phenotype due to mesothelioma tumor cell modulation
Fri Jan 08 00:00:00 EST 2016
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.
Nature immunology
Au-Yeung BB,Melichar HJ,Ross JO,Cheng DA,Zikherman J,Shokat KM,Robey EA,Weiss A
MCD0400 was used in flow cytometry to examine the quantitative and temporal requirements of Zap70's function in thymocyte development
Tue Jul 01 00:00:00 EDT 2014
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.
The Journal of experimental medicine
Velardi E,Tsai JJ,Holland AM,Wertheimer T,Yu VW,Zakrzewski JL,Tuckett AZ,Singer NV,West ML,Smith OM,Young LF,Kreines FM,Levy ER,Boyd RL,Scadden DT,Dudakov JA,van den Brink MR
MCD0400 was used in flow cytometry to analyze enhanced thymopoiesis by modulalting Notch signaling due to sex steroid blockade
Mon Nov 17 00:00:00 EST 2014
Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.
Development (Cambridge, England)
Reeh KA,Cardenas KT,Bain VE,Liu Z,Laurent M,Manley NR,Richie ER
MCD0400 was used in flow cytometry to assess the contribution of Tbx1 to thymus and parathyroid development
Fri Aug 01 00:00:00 EDT 2014
Influence of natural killer cells and perforin‑mediated cytolysis on the development of chemically induced lung cancer in A/J mice.
Cancer immunology, immunotherapy : CII
Frese-Schaper M,Keil A,Yagita H,Steiner SK,Falk W,Schmid RA,Frese S
MCD0400 was used in flow cytometry to determine which type of immune cells contributes to the protection from lung cancer development.
Sun Jun 01 00:00:00 EDT 2014
Themis sets the signal threshold for positive and negative selection in T-cell development.
Nature
Fu G,Casas J,Rigaud S,Rybakin V,Lambolez F,Brzostek J,Hoerter JA,Paster W,Acuto O,Cheroutre H,Sauer K,Gascoigne NR
MCD0400 was used in flow cytometry to describe the role of Themis in T cell development
Thu Dec 19 00:00:00 EST 2013
Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells.
Immunology letters
Fuertbauer E,Zaujec J,Uhrin P,Raab I,Weber M,Schachner H,Bauer M,Schütz GJ,Binder BR,Sixt M,Kerjaschki D,Stockinger H
MCD0400 was used in flow cytometry to characterize mice deficient in podoplanin and explore the effect of podoplanin modulation on T cell populations.
Mon Jul 14 00:00:00 EDT 2014
Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis.
PloS one
Billich A,Baumruker T,Beerli C,Bigaud M,Bruns C,Calzascia T,Isken A,Kinzel B,Loetscher E,Metzler B,Mueller M,Nuesslein-Hildesheim B,Kleylein-Sohn B
MCD0400 was used in flow cytometry to review the role of S1P lyase in T cell-mediated disease
Tue Sep 17 00:00:00 EDT 2013
Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice.
Arthritis research & therapy
Atkinson SM,Usher PA,Kvist PH,Markholst H,Haase C,Nansen A
MCD0400 was used in flow cytometry to establish and characterize a novel murine model of arthritis
Thu Jun 07 00:00:00 EDT 2012
Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy.
PloS one
Golias J,Schwarzer M,Wallner M,Kverka M,Kozakova H,Srutkova D,Klimesova K,Sotkovsky P,Palova-Jelinkova L,Ferreira F,Tuckova L
MCD0400 was used in flow cytometry to determine how thermal processing influences ovalbumin's ability to induce allergic symptoms and immune responses in mouse model of food allergy
Mon Dec 17 00:00:00 EST 2012
Adverse events post smallpox-vaccination: insights from tail scarification infection in mice with Vaccinia virus.
PloS one
Mota BE,Gallardo-Romero N,Trindade G,Keckler MS,Karem K,Carroll D,Campos MA,Vieira LQ,da Fonseca FG,Ferreira PC,Bonjardim CA,Damon IK,Kroon EG
MCD0400 was used in flow cytometry to determine the components of the host immune system that are sufficient to prevent morbidity/mortality in a murine model of smallpox
Fri Apr 15 00:00:00 EDT 2011
Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis.
PloS one
Suliman S,Tan J,Xu K,Kousis PC,Kowalski PE,Chang G,Egan SE,Guidos C
MCD0400 was used in flow cytometry to determine the importance of ligand-activated N3 in promoting beta-selection and N1 intracellular domain-induced T cell leukemogenesis
Tue Feb 28 00:00:00 EST 2012
The role of kinin receptors in preventing neuroinflammation and its clinical severity during experimental autoimmune encephalomyelitis in mice.
PloS one
Dutra RC,Leite DF,Bento AF,Manjavachi MN,Patrício ES,Figueiredo CP,Pesquero JB,Calixto JB
MCD0400 was used in flow cytometry to study the mechanisms by which the kinin receptor regulates multiple sclerosis development
Mon Apr 02 00:00:00 EDT 2012
Th17 cells are involved in the local control of tumor progression in primary intraocular lymphoma.
PloS one
Galand C,Donnou S,Crozet L,Brunet S,Touitou V,Ouakrim H,Fridman WH,Sautès-Fridman C,Fisson S
MCD0400 was used in flow cytometry to examine Th17 cells in the microenvironment of primary intraocular B-cell lymphoma
Fri Feb 03 00:00:00 EST 2012
Marginal zone precursor B cells as cellular agents for type I IFN-promoted antigen transport in autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Wang JH,Li J,Wu Q,Yang P,Pawar RD,Xie S,Timares L,Raman C,Chaplin DD,Lu L,Mountz JD,Hsu HC
MCD0400 was used in immunohistochemistry to study type I IFN and its role in regulating the migration response of antigen delivery by B cells into lymphoid follicles in autoimmune mice
Fri Jan 01 00:00:00 EST 2010
Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.
Journal of immunology (Baltimore, Md. : 1950)
Zavitz CC,Bauer CM,Gaschler GJ,Fraser KM,Strieter RM,Hogaboam CM,Stampfli MR
MCD0400 was used in flow cytometry to develop and characterize a novel model of heterologous pulmonary infection using Bordetella parapertussis and influenza virus
Mon Feb 15 00:00:00 EST 2010
Gfi1 integrates progenitor versus granulocytic transcriptional programming.
Blood
Horman SR,Velu CS,Chaubey A,Bourdeau T,Zhu J,Paul WE,Gebelein B,Grimes HL
MCD0400 was used in flow cytometry to report that Gfi1 suppresses the HoxA9-Pbx1-Meis1 progenitor program and induces a granulopoietic transcription program
Thu May 28 00:00:00 EDT 2009
Skin inflammation is not sufficient to break tolerance induced against a novel antigen.
Journal of immunology (Baltimore, Md. : 1950)
Holcmann M,Stoitzner P,Drobits B,Luehrs P,Stingl G,Romani N,Maurer D,Sibilia M
MCD0400 was used in flow cytometry to investigate immune responses to antigen in skin
Wed Jul 15 00:00:00 EDT 2009
Early infection termination affects number of CD8+ memory T cells and protective capacities in listeria monocytogenes-infected mice upon rechallenge.
Journal of immunology (Baltimore, Md. : 1950)
Tseng KE,Chung CY,H'ng WS,Wang SL
MCD0400 was used in flow cytometry to assess the effects of early termination of infection on primary T cell expansion, subsequent memory cell development, and protective immunity
Wed Apr 15 00:00:00 EDT 2009
Single cell analysis of complex thymus stromal cell populations: rapid thymic epithelia preparation characterizes radiation injury.
Clinical and translational science
Williams KM,Mella H,Lucas PJ,Williams JA,Telford W,Gress RE
MCD0400 was used in flow cytometry and immunocytochemistry to develop a new method to isolate thymic epithelial cells and study them after cytotoxic injury
Sat Aug 01 00:00:00 EDT 2009
Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Barron L,Knoechel B,Lohr J,Abbas AK
MCD0400 was used in flow cytometry to define the contributions of apoptosis and anergy to the maintenance of self-tolerance to a systemic antigen
Sat Mar 01 00:00:00 EST 2008
Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6.
Journal of immunology (Baltimore, Md. : 1950)
King SB,Knorn AM,Ohnmacht C,Voehringer D
MCD0400 was used in flow cytometry to investigate the effect of Stat6 in T cell expansion, survival, and recruitment to the lung
Tue Jan 15 00:00:00 EST 2008
Induction of experimental cerebral malaria is independent of TLR2/4/9.
Medical microbiology and immunology
Lepenies B,Cramer JP,Burchard GD,Wagner H,Kirschning CJ,Jacobs T
MCD0400 was used in flow cytometry to demonstrate that cerebral malaria development is independent of TLR2, 4 and 9
Sat Mar 01 00:00:00 EST 2008
Respiratory Francisella tularensis live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells.
Infection and immunity
Woolard MD,Hensley LL,Kawula TH,Frelinger JA
MCD0400 was used in flow cytometry to investigate how the route of inoculation with Francisella tularensis influences the primary acute adaptive immune response
Sun Jun 01 00:00:00 EDT 2008
Chitin induces accumulation in tissue of innate immune cells associated with allergy.
Nature
Reese TA,Liang HE,Tager AM,Luster AD,Van Rooijen N,Voehringer D,Locksley RM
MCD0400 was used in flow cytometry to characterize the effects of chitin on immune responses
Thu May 03 00:00:00 EDT 2007
Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Nature immunology
Taylor PR,Tsoni SV,Willment JA,Dennehy KM,Rosas M,Findon H,Haynes K,Steele C,Botto M,Gordon S,Brown GD
MCD0400 was used in flow cytometry to report that dectin-1 deficiency renders mice susceptible to infection with Candida albicans
Mon Jan 01 00:00:00 EST 2007
Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse.
Blood
Chen BJ,Deoliveira D,Cui X,Le NT,Son J,Whitesides JF,Chao NJ
MCD0400 was used in flow cytometry to propose that memory T cells respond to alloantigens initially but fail to fully develop functionally
Sun Apr 01 00:00:00 EDT 2007
IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice.
Hepatology (Baltimore, Md.)
Erhardt A,Biburger M,Papadopoulos T,Tiegs G
MCD0400 was used in flow cytometry to examine tolerance mechanisms in a concanavalin A-induced immune-mediated liver injury in mouse model
Thu Feb 01 00:00:00 EST 2007
Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1.
Cancer research
Peng J,Kitchen SM,West RA,Sigler R,Eisenmann KM,Alberts AS
MCD0400 was used in flow cytometry to indicate that defective DRF1 expression or mammalian diaphanous 1 function contributes to myeloid malignancies and suggest mammalian diaphanous 1 as an attractive therapeutic target in human myeloproliferative syndro
Wed Aug 15 00:00:00 EDT 2007
Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected.
Journal of immunology (Baltimore, Md. : 1950)
Venanzi ES,Gray DH,Benoist C,Mathis D
MCD0400 was used in flow cytometry to provide evidence that lymphotoxin pathway signals regulate development of the composition and organization of the thymus, specifically the medullary epithelial compartment
Thu Nov 01 00:00:00 EDT 2007
Characterization of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1+ CD11c+ cells as the primary IFN-gamma-expressing cells.
Infection and immunity
Chang SR,Wang KJ,Lu YF,Yang LJ,Chen WJ,Lin YH,Chang HH,Wang SL
MCD0400 was used in flow cytometry to identify the cells that are producing gamma interferon during infection with Listeria monocytogenes
Thu Mar 01 00:00:00 EST 2007
Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation.
The Journal of biological chemistry
Agrewala JN,Brown DM,Lepak NM,Duso D,Huston G,Swain SL
MCD0400 was used in flow cytometry to study the migration and persistence of naive, effector, and rested effector CD4+ T cells generated in vitro following transfer to nonimmunized adoptive hosts
Fri Mar 02 00:00:00 EST 2007
Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors.
Blood
Zhang J,Raper A,Sugita N,Hingorani R,Salio M,Palmowski MJ,Cerundolo V,Crocker PR
MCD0400 was used in flow cytometry to clone and characterize Siglec-H
Mon May 01 00:00:00 EDT 2006
Differential roles of the co-stimulatory molecules GITR and CTLA-4 in the immune response to Trichinella spiralis.
Microbes and infection
Furze RC,Culley FJ,Selkirk ME
MCD0400 was used in flow cytometry to determine the roles of the regulatory molecules glucocorticoid-induced TNF receptor family-related protein and cytotoxic T lymphocyte-associated antigen 4 in mice infected with Trichinella spiralis
Sun Oct 01 00:00:00 EDT 2006
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection.
The Journal of infectious diseases
Haque A,Easton A,Smith D,O'Garra A,Van Rooijen N,Lertmemongkolchai G,Titball RW,Bancroft GJ
MCD0400 was used in flow cytometry to study the in vivo role of cytokine- and antigen-mediated T cell activation in the resistance to Burkholderia pseudomallei
Wed Feb 01 00:00:00 EST 2006
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine.
Journal of immunology (Baltimore, Md. : 1950)
Kobie JJ,Shah PR,Yang L,Rebhahn JA,Fowell DJ,Mosmann TR
MCD0400 was used in flow cytometry to elucidate how CD73 regulates T regulatory cells and primed precursor T helper cells
Wed Nov 15 00:00:00 EST 2006
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.
Blood
Iwasaki H,Somoza C,Shigematsu H,Duprez EA,Iwasaki-Arai J,Mizuno S,Arinobu Y,Geary K,Zhang P,Dayaram T,Fenyus ML,Elf S,Chan S,Kastner P,Huettner CS,Murray R,Tenen DG,Akashi K
MCD0400 was used in flow cytometry to investigate the distinct roles that PU.1 plays in hematopoietic development
Thu Sep 01 00:00:00 EDT 2005
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Blood
Growney JD,Shigematsu H,Li Z,Lee BH,Adelsperger J,Rowan R,Curley DP,Kutok JL,Akashi K,Williams IR,Speck NA,Gilliland DG
MCD0400 was used in flow cytometry to use transgenic mice to investigate the contribution of role of Runx1 to hematopoiesis
Fri Jul 15 00:00:00 EDT 2005
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD.
Blood
Ermann J,Hoffmann P,Edinger M,Dutt S,Blankenberg FG,Higgins JP,Negrin RS,Fathman CG,Strober S
MCD0400 was used in flow cytometry to investigate the differential effect of CD62L+ and CD62L- subsets of CD4+CD25+ T regulatory cells on acute graft-versus-host disease-related mortality
Tue Mar 01 00:00:00 EST 2005
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
The Journal of experimental medicine
Iwasaki H,Mizuno S,Mayfield R,Shigematsu H,Arinobu Y,Seed B,Gurish MF,Takatsu K,Akashi K
MCD0400 was used in flow cytometry to elucidate the cellular mechanisms by which granulocyte/monocyte progenitors give rise to eosinophils
Mon Jun 20 00:00:00 EDT 2005
Involvement of the immune response in the cure of metastatic murine CT-26 colon carcinoma by low electric field-enhanced chemotherapy.
International journal of cancer
Plotnikov A,Tichler T,Korenstein R,Keisari Y
MCD0400 was used in flow cytometry to investigate the efficacy of low electric field cancer treatment-enhanced chemotherapy
Sat Dec 10 00:00:00 EST 2005
Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage.
Journal of immunology (Baltimore, Md. : 1950)
Kohu K,Sato T,Ohno S,Hayashi K,Uchino R,Abe N,Nakazato M,Yoshida N,Kikuchi T,Iwakura Y,Inoue Y,Watanabe T,Habu S,Satake M
MCD0400 was used in flow cytometry to report that Runx3 drives thymocytes to select the CD4-8+ lineage
Tue Mar 01 00:00:00 EST 2005
Comparative dynamics and phenotype of the murine immune response to Trichinella spiralis and Trichinella pseudospiralis.
Parasite immunology
Furze RC,Selkirk ME
MCD0400 was used in flow cytometry to compare the immune responses of mice infected with Trichinella spiralis or Trichinella pseudospiralis
Sun May 01 00:00:00 EDT 2005
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
Blood
Chen BJ,Cui X,Sempowski GD,Domen J,Chao NJ
MCD0400 was used in flow cytometry to test if higher numbers of hematopoietic stem cells correlate with the speed of immune reconstitution in a congenic transplantation mouse model
Tue Jun 01 00:00:00 EDT 2004
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.
The Journal of experimental medicine
van Santen HM,Benoist C,Mathis D
MCD0400 was used in flow cytometry to investigate the differentiation of CD4+CD25+ regulatory T cells
Mon Nov 15 00:00:00 EST 2004
A transgenic mouse model genetically tags all activated CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Maris CH,Miller JD,Altman JD,Jacob J
MCD0400 was used in flow cytometry to track the dynamics of the antiviral CD8+ T cell responses using a transgenic mouse that marks activated T cells.
Mon Sep 01 00:00:00 EDT 2003
Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthood.
The Journal of experimental medicine
Culley FJ,Pollott J,Openshaw PJ
MCD0400 was used in flow cytometry to study the effect of infection age using severe respiratory syncytial virus.
Mon Nov 18 00:00:00 EST 2002
Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand.
Journal of immunology (Baltimore, Md. : 1950)
Batteux F,Tourneur L,Trebeden H,Charreire J,Chiocchia G
MCD0400 was used in flow cytometry to study FasL expression on thyrocytes.
Fri Jan 01 00:00:00 EST 1999