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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 17 and 305 of Human MCM5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29913 targets MCM5 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29913 immunogen is recombinant fragment corresponding to a region within amino acids 17 and 305 of Human MCM5.
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CDC46; CDC46 homolog; cell division cycle 46; MCM5 minichromosome maintenance deficient 5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5 (cell division cycle 46)
CDC46; MCM5; P1-CDC46