This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: double minute 1; Mdm1 nuclear protein homolog; Mdm4 transformed 3T3 cell double minute 1 protein; Mdm4, transformed 3T3 cell double minute 1, p53 binding protein; Mouse double minute 1; nuclear protein double minute 1; Nuclear protein MDM1; transformed mouse 3T3 cell double minute 1
Gene Aliases: Arrd2; Mdm-1; MDM1