Product References
Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance.
The EMBO journal
Garcia-Carpio I,Braun VZ,Weiler ES,Leone M,Niñerola S,Barco A,Fava LL,Villunger A
Published figure using MDM2 monoclonal antibody (Product # MA1-113) in Western Blot
Mon Oct 16 00:00:00 EDT 2023
Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c-Myc and p53 substrates in patients with dysplastic nevi or melanoma.
Oncology letters
Mozuraitiene J,Gudleviciene Z,Vincerzevskiene I,Laurinaviciene A,Pamedys J
MA1-113 was used in Immunohistochemistry to determine the expression levels of F-box and WD repeat domain-containing 7 (FBXW7), c-Myc, MDM2 and p53 proteins in samples from patients with dysplastic nevi or melanoma, and to evaluate their association with clinicopathological parameters and prognosis of the disease.
Fri Jan 01 00:00:00 EST 2021
Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c-Myc and p53 substrates in patients with dysplastic nevi or melanoma.
Oncology letters
Mozuraitiene J,Gudleviciene Z,Vincerzevskiene I,Laurinaviciene A,Pamedys J
MA1-113 was used in Immunohistochemistry to determine the expression levels of F-box and WD repeat domain-containing 7 (FBXW7), c-Myc, MDM2 and p53 proteins in samples from patients with dysplastic nevi or melanoma, and to evaluate their association with clinicopathological parameters and prognosis of the disease.
Fri Jan 01 00:00:00 EST 2021
Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Molecular cell
Müller I,Strozyk E,Schindler S,Beissert S,Oo HZ,Sauter T,Lucarelli P,Raeth S,Hausser A,Al Nakouzi N,Fazli L,Gleave ME,Liu H,Simon HU,Walczak H,Green DR,Bartek J,Daugaard M,Kulms D
MA1-113 was used in Immunocytochemistry to identify a non-canonical role of caspase-8 exploited by cancer cells to override the p53-dependent G2/M cell-cycle checkpoint.
Thu Mar 05 00:00:00 EST 2020
Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Molecular cell
Müller I,Strozyk E,Schindler S,Beissert S,Oo HZ,Sauter T,Lucarelli P,Raeth S,Hausser A,Al Nakouzi N,Fazli L,Gleave ME,Liu H,Simon HU,Walczak H,Green DR,Bartek J,Daugaard M,Kulms D
MA1-113 was used in Immunocytochemistry to identify a non-canonical role of caspase-8 exploited by cancer cells to override the p53-dependent G2/M cell-cycle checkpoint.
Thu Mar 05 00:00:00 EST 2020
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO reports
Sladky VC,Knapp K,Szabo TG,Braun VZ,Bongiovanni L,van den Bos H,Spierings DC,Westendorp B,Curinha A,Stojakovic T,Scharnagl H,Timelthaler G,Tsuchia K,Pinter M,Semmler G,Foijer F,de Bruin A,Reiberger T,Rohr-Udilova N,Villunger A
Published figure using MDM2 monoclonal antibody (Product # MA1-113) in Western Blot
Thu Dec 03 00:00:00 EST 2020
MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes.
Cancer research
Casadei L,Calore F,Braggio DA,Zewdu A,Deshmukh AA,Fadda P,Lopez G,Wabitsch M,Song C,Leight JL,Grignol VP,Lev D,Croce CM,Pollock RE
MA1-113 was used in Western Blotting to demonstrate that that MDM2 plays a crucial role in DDLPS by enabling crosstalk between tumor cells and the surrounding microenvironment.
Tue Oct 01 00:00:00 EDT 2019
Dual Targeting of Aurora Kinases with AMG 900 Exhibits Potent Preclinical Activity Against Acute Myeloid Leukemia with Distinct Post-Mitotic Outcomes.
Molecular cancer therapeutics
Payton M,Cheung HK,Ninniri MSS,Marinaccio C,Wayne WC,Hanestad K,Crispino JD,Juan G,Coxon A
MA1-113 was used in Western Blotting to study the dual targeting of aurora kinases with AMG 900 in acute myeloid leukaemia.
Sat Dec 01 00:00:00 EST 2018
Dual Targeting of Aurora Kinases with AMG 900 Exhibits Potent Preclinical Activity Against Acute Myeloid Leukemia with Distinct Post-Mitotic Outcomes.
Molecular cancer therapeutics
Payton M,Cheung HK,Ninniri MSS,Marinaccio C,Wayne WC,Hanestad K,Crispino JD,Juan G,Coxon A
MA1-113 was used in Western Blotting to study the dual targeting of aurora kinases with AMG 900 in acute myeloid leukaemia.
Sat Dec 01 00:00:00 EST 2018
Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Saâda-Bouzid E,Burel-Vandenbos F,Ranchère-Vince D,Birtwisle-Peyrottes I,Chetaille B,Bouvier C,Château MC,Peoc'h M,Battistella M,Bazin A,Gal J,Michiels JF,Coindre JM,Pedeutour F,Bianchini L
MA1-113 was used in immunohistochemistry to investigate the frequency and contribution of HMGA2, CDK4, and JUN to dedifferentiated liposarcomas and atypical lipomatous tumors/well-differentiated liposarcomas.
Sun Nov 01 00:00:00 EDT 2015
Myxoid liposarcoma with heterologous components: dedifferentiation or metaplasia? A FISH-documented and CGH-documented case report.
Applied immunohistochemistry & molecular morphology : AIMM
Weingertner N,Neuville A,Chibon F,Ray-Coquard I,Marcellin L,Ghnassia JP
MA1-113 was used in immunohistochemistry - paraffin section to characterize a primary myxoid liposarcoma with chondroid and osseous components
Sun Mar 01 00:00:00 EST 2015
MDM2 and CDK4 immunohistochemical coexpression in high-grade osteosarcoma: correlation with a dedifferentiated subtype.
The American journal of surgical pathology
Yoshida A,Ushiku T,Motoi T,Beppu Y,Fukayama M,Tsuda H,Shibata T
MA1-113 was used in immunohistochemistry (paraffin) to discuss markers that distinguish between different subtypes of osteosarcomas.
Thu Mar 01 00:00:00 EST 2012
MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Dujardin F,Binh MB,Bouvier C,Gomez-Brouchet A,Larousserie F,Muret Ad,Louis-Brennetot C,Aurias A,Coindre JM,Guillou L,Pedeutour F,Duval H,Collin C,de Pinieux G
MA1-113 was used in immunohistochemistry to examine expression of MDM2-CDK4 in low-grade osteosarcomas and fibrous or fibro-osseous lesions of the bone or paraosseous soft tissue.
Sun May 01 00:00:00 EDT 2011
Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Yoshida A,Ushiku T,Motoi T,Shibata T,Beppu Y,Fukayama M,Tsuda H
MA1-113 was used in immunohistochemistry - paraffin section to explore the use of MDM2 and CDK4 for the histological diagnosis of low-grade osteosarcoma
Wed Sep 01 00:00:00 EDT 2010
Well-differentiated liposarcoma with low-grade osteosarcomatous component: an underrecognized variant.
The American journal of surgical pathology
Yoshida A,Ushiku T,Motoi T,Shibata T,Fukayama M,Tsuda H
MA1-113 was used in immunohistochemistry - paraffin section to use 9 cases of well-differentiated/dedifferentiated liposarcoma to characterize unappreciated features
Wed Sep 01 00:00:00 EDT 2010
Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Horvai AE,DeVries S,Roy R,O'Donnell RJ,Waldman F
MA1-113 was used in immunohistochemistry - paraffin section to report genetic changes in dedifferentiated liposarcomas
Sun Nov 01 00:00:00 EDT 2009
Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Daugaard S,Christensen LH,Høgdall E
MA1-113 was used in immunohistochemistry - paraffin section to identify immunohistochemical markers to aid chondroid tumor diagnosis
Wed Jul 01 00:00:00 EDT 2009
Lipoleiomyosarcoma of the rectosigmoid colon: a unique site for a rare variant of liposarcoma.
American journal of clinical oncology
Nahal A,Meterissian S
MA1-113 was used in immunohistochemistry to discuss a rare presentation of a lipoleiomyosarcoma and review the method of pathologic diagnosis
Sat Aug 01 00:00:00 EDT 2009
Immunostaining for peroxisome proliferator gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Horvai AE,Schaefer JT,Nakakura EK,O'Donnell RJ
MA1-113 was used in immunohistochemistry - paraffin section to assess if immunostaining for PPAR-gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas
Thu May 01 00:00:00 EDT 2008
Sporadic desmoid tumor. An exceptional cause of cystic pancreatic lesion.
JOP : Journal of the pancreas
Amiot A,Dokmak S,Sauvanet A,Vilgrain V,Bringuier PP,Scoazec JY,Sastre X,Ruszniewski P,Bedossa P,Couvelard A
MA1-113 was used in immunohistochemistry to discuss the properties of desmoid tumors
Thu May 08 00:00:00 EDT 2008
alpha-fetoprotein expression in a dedifferentiated liposarcoma.
Virchows Archiv : an international journal of pathology
Bosco M,Allia E,Coindre JM,Odasso C,Pagani A,Pacchioni D
MA1-113 was used in immunohistochemistry - paraffin section to present a unique case of relapsing retroperitoneal dedifferentiated liposarcoma with alpha-fetoprotein ectopic production
Sat Apr 01 00:00:00 EST 2006
Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location.
Virchows Archiv : an international journal of pathology
Mentzel T,Toennissen J,Rütten A,Schaller J
MA1-113 was used in immunohistochemistry - paraffin section to present the case of a patient with a rare atypical lipomatous tumor with spindle cell features
Tue Mar 01 00:00:00 EST 2005
Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity.
The Journal of pathology
Coindre JM,Hostein I,Maire G,Derré J,Guillou L,Leroux A,Ghnassia JP,Collin F,Pedeutour F,Aurias A
MA1-113 was used in immunohistochemistry (frozen) to characterize dedifferentiated liposarcomas with an inflammatory malignant fibrous histiocytoma component.
Thu Jul 01 00:00:00 EDT 2004
Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: a review of 25 cases initially diagnosed as malignant fibrous histiocytoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Coindre JM,Mariani O,Chibon F,Mairal A,De Saint Aubain Somerhausen N,Favre-Guillevin E,Bui NB,Stoeckle E,Hostein I,Aurias A
MA1-113 was used in immunohistochemistry (paraffin) to report that most so-called malignant fibrous histiocytomas from the retroperitoneum are dedifferentiated liposarcoma.
Sat Mar 01 00:00:00 EST 2003