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          • Primary Antibodies ›
          • ME2 Antibodies

          Rockland

          ME2 Polyclonal Antibody

          View all (9) ME2 antibodies

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          Cite ME2 Polyclonal Antibody

          Additional Information:

          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

          Product Details

          600-401-CS9

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          5 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          20 µg/mL
          -

          ELISA (ELISA)

          1:10,000-1:20,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Anti-ME2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the internal region of human ME2.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.2

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2, NAD(+)-dependent, mitochondrial; NAD-ME; pyruvic-malic carboxylase; unnamed protein product

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          Gene Aliases: ODS1

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          UniProt ID: (Human) P23368

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          Entrez Gene ID: (Human) 4200

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          Function(s)
          malic enzyme activity malate dehydrogenase (decarboxylating) (NAD+) activity malate dehydrogenase (decarboxylating) (NADP+) activity oxaloacetate decarboxylase activity electron carrier activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor NAD binding
          Process(es)
          regulation of NADP metabolic process
          It has to be done as per old AB suggested Products section.

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