This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: DVSLRIAIKV LDYAYKHNLA SYYPEPKDKE AFVRSLVYTP DYDSFTLDSY TWPKEAMNVQ TV
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 76%.
ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HME; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Malic enzyme 3; malic enzyme 3, NADP(+)-dependent, mitochondrial; malic enzyme, NADP+-dependent, mitochondrial; mitochondrial NADP(+)-dependent malic enzyme 3; MMP3; NADP-dependent malic enzyme, mitochondrial; NADP-ME; pyruvic-malic carboxylase
Gene Aliases: ME3; NADP-ME
UniProt ID: (Human) Q16798
Entrez Gene ID: (Human) 10873
Molecular Function: oxidoreductase