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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 17 amino acid peptide from near the carboxy terminus of human MED4.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||10 µg/ml|
|Western Blot (WB)||0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is human testis tissue lysate.
PA5-20571 can be used with blocking peptide PEP-0691.
The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
activator-recruited cofactor 36 kDa component; mediator of RNA polymerase II transcription subunit 4; mediator of RNA polymerase II transcription, subunit 4 homolog; mediator, 34-kD subunit, homolog; p36 TRAP/SMCC/PC2 subunit; RP11-90M2.2, ARC36, DRIP36, HSPC126, TRAP36, VDRIP; TRAP/SMCC/PC2 subunit p36; vitamin D receptor interacting protein; vitamin D receptor-interacting protein, 36-kD; vitamin D3 receptor-interacting protein complex 36 kDa component
2410046H15Rik; ARC36; DRIP36; HSPC126; MED4; TRAP36; Vdirp; VDRIP