This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: QQHQALQTNW HLPQMSSPPS AARHSLCLQP DSGGPPELGS SPPVLCSNSS SLGSSTPTGA ACAPGDYGRQ ALSPAEAEKR SGGKR
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GAX; Growth arrest-specific homeobox; Homeobox protein MOX-2; MEOX2; Mesenchyme homeobox 2; MOX2
Gene Aliases: GAX; MEOX2; MOX2
UniProt ID: (Human) P50222
Entrez Gene ID: (Human) 4223