This gene encodes a 25-kDa microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31- kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2.
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Protein Aliases: MAGP-2; MFAP-5; Microfibril-associated glycoprotein 2; microfibril-associated glycoprotein-2; Microfibrillar-associated protein 5; MP25; THE1A-MFAP5
Gene Aliases: AAT9; MAGP-2; MAGP2; MFAP-5; MFAP5; MP25