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Positive test controls include: Mouse liver, Mouse kidney, Mouse heart, Rat liver. The target is usually found in the following locations: Golgi apparatus membrane, Single-pass type II membrane protein.
Immunogen sequence: GSAVTHIRQP DLSSIAVPPD HRKFQGYYKI ARHYRWALGQ VFRQFRFPAA VVVEDDLEVA PDFFEYFRAT YPLLKADPSL WCVSAWNDNG KEQMVDASRP ELLYRTDFFP GLGWLLLAEL WAELEPKWPK AFWDDWMRRP EQRQGRACIR PEISRTMTFG RKGVSHGQFF DQHLKFIKLN QQFVHFTQLD LSYLQREAYD RDFLARVYGA PQLQVEKVRT NDRKELGEVR VQYTGRDSFK AFAKALGVMD DLKSGVPRAG YRGIVTFQFR GRRVHLAPPL TWEGYDPSWN
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; GNT-I; mannoside acetylglucosaminyltransferase 1; MGAT1 gene for N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; OTTHUMP00000161546
Gene Aliases: GGNT1; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; Gnt1; GnTI; MGAT; Mgat-1; MGAT1
UniProt ID: (Human) P26572, (Rat) Q09325, (Mouse) P27808
Entrez Gene ID: (Human) 4245, (Rat) 81519, (Mouse) 17308
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