This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.
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Protein Aliases: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; OTTHUMP00000161546
Gene Aliases: GGNT1; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT; MGAT1
UniProt ID: (Human) B3KRU8
Entrez Gene ID: (Human) 4245