Immunogen sequence: SDTLALPRHC LLGWDIFPPK SEKSSAPRNL DLWSSVSAEA QHQKLSGTSS PFHPASPMQM LPPTPTWSVP QVPRPHVPRQ KP
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 53%.
MIIP inhibits glioma cells invasion and down-regulates adhesion-and motility-associated genes such as NFKB2 and ICAM1. MIIP exhibits opposing effects to IGFBP2 on cell invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IGFBP2-binding protein; IIp45; Invasion-inhibitory protein 45; Migration and invasion-inhibitory protein
Gene Aliases: IIP45; MIIP
UniProt ID: (Human) Q5JXC2
Entrez Gene ID: (Human) 60672