This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: EQEKRAQQPA PAPAPLGTPV KQENSFSSCQ LSQQPLGPAH PFNPSLAAPA TNHIDPCAVA PGPPSVVVKQ EALQPEPEPV PAPQLLLGPQ GPSLIKGVAP PTLITDSTGT HLVLTVTNKN ADSPG
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 66%.
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: basic, SAP and coiled-coil domain; BSAC; MAL; Megakaryoblastic leukemia 1 protein; megakaryoblastic leukemia translocation 1; Megakaryocytic acute leukemia protein; MKL/myocardin-like protein 1; MRTF-A; Myocardin-related transcription factor A
Gene Aliases: BSAC; KIAA1438; MAL; MKL1; MRTF-A; MRTFA
UniProt ID: (Human) Q969V6
Entrez Gene ID: (Human) 57591
Molecular Function: transcription factor