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Proteintech
MLYCD Polyclonal Antibody
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Product Details
15265-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MLYCD Fusion Protein Ag7334 (142-493 aa encoded by BC000286)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: HHISKLDGG VRFLVQLRAD LLEAQALKLV EGPDVREMNG VLKGMLSEWF SSGFLNLERV TWHSPCEVLQ KISEAEAVHP VKNWMDMKRR VGPYRRCYFF SHCSTPGEPL VVLHVALTGD ISSNIQAIVK EHPPSETEEK NKITAAIFYS ISLTQQGLQG VELGTFLIKR VVKELQREFP HLGVFSSLSP IPGFTKWLLG LLNSQTKEHG RNELFTDSEC KEISEITGGP INETLKLLLS SSEWVQSEKL VRALQTPLMR LCAWYLYGEK HRGYALNPVA NFHLQNGAVL WRINWMADVS LRGITGSCGL MANYRYFLEE TGPNSTSYLG SKIIKASEQV LSLVAQFQKN SKL (142-493 aa encoded by BC000286)
Target Information
MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: malonyl coenzyme A decarboxylase; Malonyl-CoA decarboxylase, mitochondrial; MCD
Gene Aliases: AI324784; MCD; MLYCD
UniProt ID: (Human) O95822, (Rat) Q920F5, (Mouse) Q99J39
Entrez Gene ID: (Human) 23417, (Rat) 85239, (Mouse) 56690
response to ischemia
acetyl-CoA biosynthetic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
acyl-CoA metabolic process
response to nutrient
regulation of glucose metabolic process
fatty acid oxidation
regulation of fatty acid beta-oxidation
regulation of fatty acid oxidation
positive regulation of fatty acid oxidation
malonyl-CoA catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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