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Proteintech
MPO Polyclonal Antibody
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FIGURE: 1 / 2
MPO Antibody (32385-1-AP) in IHC (P)
Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using MPO antibody (32385-1-AP) at dilution of 1:200 and CoraLite488-Conjugated Goat Anti-Rabbit IgG (H+L) (SA,00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
32385-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Concentration
500 µg/mL
Amount
75 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MLQTSNGATP ALLGEVENSV VLSCMEEAKQ LVDRAYKERR ESIKRSLQSG SASPTELLFY FKQPVAGTRT AVRAADYLHV ALDLLKRKLQ PLWPRPFNVT DVLTPAQLNL LSVSSGCAYQ DVGVTCPPND KYRTITGHCN NRRSPTLGAS NRAFVRWLPA EYEDGVSMPF GWTPGVNRNG FKVPLARQVS NAIVRFPNDQ LTKDQERALM FMQWGQFLDH DITLTPEPAT RFSFFTGLNC ETSCLQQPPC FPLKIPPNDP RIKNQKDCIP FFRSCPACTR NNITIRNQIN ALTSFVDASG VYGSEDPLAR KLRNLTNQLG LLAVNTRFQD NGRALMPFDS LHDDPCLLTN RSARIPCFLA GDMRSSEMPE LTSMHTLFVR EHNRLATQLK RLNPRWNGEK LYQEARKIVG AMVQIITYRD YLPLVLGPAA MKKYLPQYRS YNDSVDPRIA NVFTNAFRYG HTLIQPFMFR LNNQYRPTGP NPRVPLSKVF FASWRVVLEG GIDPILRGLM ATPAKLNRQN QIVVDEIRER LFEQVMRIGL DLPALNMQRS RDHGLPGYNA WRRFCGLPQP STVGELGTVL KNLELARKLM AQYGTPNNID IWMGGVSEPL EPNGRVGQLL ACLIGTQFRK LRDGDRFWWE NPGVFSKQQR QALASISLPR IICDNTGITT VSKNNIFMSN TYPRDFVSCN TLPKLNLTSW KET
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MPO; Myeloperoxidase
Gene Aliases: mKIAA4033; Mpo
UniProt ID: (Mouse) P11247
Entrez Gene ID: (Rat) 303413, (Mouse) 17523
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
aging
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
hydrogen peroxide catabolic process
negative regulation of growth of symbiont in host
defense response to Gram-positive bacterium
defense response to fungus
oxidation-reduction process
response to gold nanoparticle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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