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Immunogen sequence: KESKVFMRA LFHYNPREDR AIPCQEAGLP FQRRQVLEVV SQDDPTWWQA KRVGDTNLRA GLIPSKGFQE RRLSYRRAAG TLPSPQSLRK PPYDQPCDKE TCDCEGYLKG HYVAGLRRSF RLGCRERLGG SQEGKMSSGA ESPELLTYEE VARYQHQPGE RPRLVVLIGS LGARLHELKQ KVVAENPQHF GVAVPHTTRP RKSHEKEGVE YHFVSKQAFE ADLHHNKFLE HGEYKENLYG TSLEAIQAVM AKNKVCLVDV EPEALKQLRT SEFKPYIIFV KPAIQEKRKT PPMSPACEDT AAPFDEQQQE MAASAAFIDR HYGHLVDAVL VKEDLQGAYS QLKVVLEKLS KDTHWVPVSW VR (225-585 aa encoded by BC056865)
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Discs large homolog 3; discs, large homolog 3; MAGUK p55 subfamily member 3; MAGUK p55 subfamily member 3 {ECO:0000250|UniProtKB:O88910}; membrane protein palmitoylated 3; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3); Mpp3 membrane protein, palmitoylated 3; mpp3 {ECO:0000312|RGD:620015}; protein Dlgh3; Protein MPP3
Gene Aliases: 6430514B01; CSG18; DLG3; Dlgh3; Dusp3; MPP3
UniProt ID: (Human) Q13368, (Rat) O88954
Entrez Gene ID: (Human) 4356, (Rat) 114202, (Mouse) 13384
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