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Invitrogen
MRG Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-53534
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MRG. Recombinant protein control fragment (Product #RP-89545).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644102
Product Specific Information
Immunogen sequence: LFHAMLGHKP VGVNRHFHMI CIRDKFSQNI GRQVPSKVIW DHLSTMYDMQ ALHESEILPF PNPERNFVLP EEIIQEVREG KVMIEEEMKE EMKEDVDPHN GADDVFSSSG SLGKASEKSS KDKEKNSSDL GCKE
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
C20orf20, also named as MRG/MORF4L-binding protein or Up-regulated in colon cancer 4 (Urcc4), is a 204 amino acid protein, which belongs to the EAF7 family. C20orf20 localizes in the nucleus and is a Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. C20orf20 is modified through phosphorylation and acetylation, so the molecular weight of C20orf20 might be 25-30 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ10914; MRG-binding protein; MRG/MORF4L-binding protein; Up-regulated in colon cancer 4; Urcc4
Gene Aliases: 1600027N09Rik; AW060503; C20orf20; C80444; Eaf7; MRG15BP; MRGBP; RGD1308612; URCC4
UniProt ID: (Human) Q9NV56, (Mouse) Q9DAT2
Entrez Gene ID: (Human) 55257, (Mouse) 73247, (Rat) 311713
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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