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Proteintech
MRP2 Polyclonal Antibody
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Product Details
29261-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: ETDNLIQTTI QNEFAHCTVI TIAHRLHTIM DSDKVMVLDN GKIIECGSPE ELLQIPGPFY FMAKEAGIEN VNSTKF
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette sub-family C member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Human MRP2; KIAA1010; Multidrug resistance-associated protein 2
Gene Aliases: ABC30; ABCC2; CMOAT; CMOAT1; CMRP; DJS; MRP2
UniProt ID: (Human) Q92887
Entrez Gene ID: (Human) 1244
protein binding
ATP binding
organic anion transmembrane transporter activity
bilirubin transmembrane transporter activity
protein domain specific binding
ATPase activity, coupled to transmembrane movement of substances
anion transmembrane-transporting ATPase activity
ATP-binding cassette (ABC) transporter
transport
drug transmembrane transport
response to oxidative stress
response to heat
bilirubin transport
prostaglandin transport
cellular chloride ion homeostasis
response to methotrexate
response to estrogen
response to arsenic-containing substance
response to steroid hormone
transmembrane transport
thyroid hormone transport
anion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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