Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 4 publications 4 publications |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MRPL23 Fusion Protein Ag2220 (1-153 aa encoded by BC027710) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.17 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MARNVVYPL YRLGGPQLRV FRTNFFIQLV RPGVAQPEDT VQFRIPMEMT RVDLRNYLEG IYNVPVAAVR TRVQHGSNKR RDHRNVRIKK PDYKVAYVQL AHGQTFTFPD LFPEKDESPE GSAADDLYSM LEEERQQRQS SDPRRGGVPS WFGL (1-153 aa encoded by BC027710)
MRPL23 are mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL23 encodes a 39S subunit protein and is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L23, mitochondrial; FLJ45387; L23 mitochondrial-related protein; L23mt; Mitochondrial large ribosomal subunit protein uL23m; MRP-L23; Ribosomal protein L23-like; ribosomal protein related to L23 (mitochondrial)
Gene Aliases: L23MRP; MRPL23; RPL23; RPL23L
UniProt ID: (Human) Q16540
Entrez Gene ID: (Human) 6150
Molecular Function:
ribosomal protein
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