Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: ANERPRHHH VMPHANMNVH YIPAEKNVDL CKEMVDGLRI TFDYTLPLVL LYPYEQAQYK KVTSSKFFLP IKESATSTNR SQEELSPSPP LLNPSTPQST ESQPTTGEPA TPKRRKAEPE ALQSLRRSTR HSANCDRLSE SSASPQPKRR QQDTSASMPK LFLHLEKKTP VHSRSSSPIP LTPSKEGSAV FAGFEGRRTN EINEVLSWKL VPDNYPPGDQ PPPPSYIYGA QHLLRLFVKL PEILGKMSFS EKNLKALLKH FDLFLRFLAE YHDDFFPESA YVAACEAHYS TKNPRAIY (225-521 aa encoded by BC031210)
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL complex subunit 3; MSL3-like 1
Gene Aliases: AU018931; MSL3; Msl31; MSL3L1
UniProt ID: (Human) Q8N5Y2, (Mouse) Q9WVG9
Entrez Gene ID: (Human) 10943, (Mouse) 17692, (Rat) 317464
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