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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MSL3 Antibodies

          Invitrogen

          MSL3 Polyclonal Antibody

          View all (4) MSL3 antibodies

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          Cite MSL3 Polyclonal Antibody

          • Antibody Testing Data (4)
          MSL3 Antibody in Immunocytochemistry (ICC/IF)
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          MSL3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          MSL3 Antibody (PA5-28282) in ICC/IF

          MSL3 Polyclonal Antibody detects MSL3L1 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MSL3L1 protein stained by MSL3 Polyclonal Antibody (Product # PA5-28282) diluted at 1:500. Blue: Hoechst 33342 staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MSL3 Antibody in Immunocytochemistry (ICC/IF)
          MSL3 Antibody in Western Blot (WB)
          MSL3 Antibody in Western Blot (WB)
          MSL3 Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-28282

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          -

          Immunoprecipitation (IP)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human MSL3L1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 1% BSA, 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545758

          Product Specific Information

          Recommended positive controls: 293T, mouse muscle.

          Predicted reactivity: Mouse (95%), Rat (94%), Xenopus laevis (80%), Pig (96%), Bovine (94%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL complex subunit 3; MSL3-like 1

          View more View less

          Gene Aliases: AU018931; MSL3; Msl31; MSL3L1

          View more View less

          UniProt ID: (Human) Q8N5Y2, (Mouse) Q9WVG9

          View more View less

          Entrez Gene ID: (Human) 10943, (Mouse) 17692

          View more View less

          Function(s)
          DNA binding methylated histone binding chromatin/chromatin-binding, or -regulatory protein
          Process(es)
          chromatin remodeling chromatin silencing transcription, DNA-templated chromatin modification histone deacetylation histone H2A acetylation histone H4-K16 acetylation regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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