Peptide sequence: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE
Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 91%; Rat: 91%
Msx2 is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in the Msx2 gene are associated with parietal foramina 1 and craniosynostosis type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeo box, msh-like 2; Homeobox protein Hox-8; Homeobox protein Hox-8-1; Homeobox protein MSX-2; homeobox, msh-like 2; hox-8.1; msh homeo box 2; msh homeo box homolog 2; msh homeobox 1-like; msh homeobox homolog 2; muscle segmentation homologue (MSX2)
Gene Aliases: BB122635; BOS_19668; CRS2; FPP; Hox-8; Hox-8.1; HOX8; Hox8.1; MSH; Msx-2; MSX2; PFM; PFM1