Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.2-1 µg/mL | - |
Immunocytochemistry (ICC/IF) |
4 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide directed towards the N-terminal of human MSX2 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2608897 |
Peptide sequence: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE
Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 91%; Rat: 91%
Msx2 is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in the Msx2 gene are associated with parietal foramina 1 and craniosynostosis type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeo box, msh-like 2; Homeobox protein Hox-8; Homeobox protein Hox-8-1; Homeobox protein MSX-2; homeobox, msh-like 2; msh homeo box 2; msh homeobox homolog 2
Gene Aliases: BB122635; CRS2; FPP; Hox-8; Hox-8.1; HOX8; Hox8.1; MSH; Msx-2; MSX2; PFM; PFM1
UniProt ID: (Human) P35548, (Mouse) Q03358
Entrez Gene ID: (Human) 4488, (Mouse) 17702
Molecular Function:
homeodomain transcription factor
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