Immunogen sequence: ARQTPHLGEQ RRTTASLLRK LTTASNGGVI EELSCVRSNN YVQEPECRRN LVQCLLEKQG TPVVQGSLEL ERVMSSLLDM GFSNAHINEL LSVRRGASLQ QLLDIISEFI LLGLNPEPVC VVLKKSPQLL
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 55%.
Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
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Protein Aliases: Mitochondrial transcription termination factor 4; MTERF domain containing 2; mTERF domain-containing protein 2; mTERF domain-containing protein 2 processed; Transcription termination factor 4, mitochondrial
Gene Aliases: HSPC096; MTERF4; MTERFD2
UniProt ID: (Human) Q7Z6M4
Entrez Gene ID: (Human) 130916