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Abnova
MTHFD2 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00010797-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MTHFD2 (NP_001035499.1, 1 a.a. approximately 248 a.a) full-length human protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKPASISEEE LLNLINKLNN DDNVDGLLVQ LPLPEHIDER RICNAVSPDK DVDGFHVINV GRMCLDQYSM LPATPWGVWE IIKRTGIPTL GKNVVVAGRS KNVGMPIAML LHTDGAHERP GGDATVTISH RYTPKEQLKK HTILADIVIS AAGIPNLITA DMIKEGAAVI DVGINRVHDP VTAKPKLVGD VDFEGVRQKA GYITPVPGGV GPMTVAMLMK NTIIAAKKVL RLEEREVLKS KELGVATN
Target Information
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; unnamed protein product
Gene Aliases: NMDMC
UniProt ID: (Human) P13995
Entrez Gene ID: (Human) 10797
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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