Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:5,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
ELISA (ELISA) |
Assay-Dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant Human Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial protein (40-250AA) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.23 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2812600 |
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Methenyltetrahydrofolate cyclohydrolase; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; NAD-dependent methylenetetrahydrofolate dehydrogenase
Gene Aliases: MTHFD2; NMDMC
UniProt ID: (Human) P13995
Entrez Gene ID: (Human) 10797
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
