Recommended positive controls: A549, HepG2.
Predicted reactivity: Mouse (85%), Rat (85%), Rhesus Monkey (95%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5,10-methenyl-tetrahydrofolate synthetase; 5-formyltetrahydrofolate cyclo-ligase; FLJ30410; methenyl-THF synthetase; MTHFS
Gene Aliases: HsT19268; MTHFS
UniProt ID: (Human) P49914
Entrez Gene ID: (Human) 10588
Molecular Function: ligase