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Immunogen sequence: MAGARAAAAA ASAGSSASSG NQPPQELGLG ELLEEFSRTQ YRAKDGSGTG GSKVERIEKR CLELFGRDYC FSVIPNTNGD ICGHYPRHIV FLEYESSEKE KDTFESTVQV SKLQDLIHRS KMARCRGRFV CPVILFKGKH ICRSATLAGW GELYGRSGYN YFFSGGADDA WADVEDVTEE DCALRSGDTH LFDKVRGYDI KLLRYLSVKY ICDLMVENKK VKFGMNVTSS EKVDKAQRYA DFTLLSIPYP GCEFFKEYKD RDYMAEGLIF NWKQDYVDAP; Positive Samples: BT-474, Jurkat, Mouse liver, Mouse spleen, Mouse testis, Rat brain; Cellular Location: Cytoplasm
Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hJumpy; jumpy; mJumpy; Myotubularin-related protein 14; NS5ATP4ABP1
Gene Aliases: 1110061O04Rik; AW553738; C3orf29; C76151; MTMR14; RGD1304842
UniProt ID: (Human) Q8NCE2, (Mouse) Q8VEL2
Entrez Gene ID: (Human) 64419, (Mouse) 97287, (Rat) 312634
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