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Invitrogen

MTMR14 Polyclonal Antibody

View all (22) MTMR14 antibodies
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Product Details

PA5-96694

Applications Tested Dilution Publications

Western Blot (WB)

 1:500-1:2,000 -
Product Specifications

Species Reactivity

 Human, Mouse, Rat

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MTMR14.
View antigen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 4.92 mg/mL

Purification

 Antigen affinity chromatography

Storage buffer

 PBS, pH 7.3, with 50% glycerol

Contains

 0.02% sodium azide

Storage conditions

 -20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2808496

Product Specific Information

Immunogen sequence: MAGARAAAAA ASAGSSASSG NQPPQELGLG ELLEEFSRTQ YRAKDGSGTG GSKVERIEKR CLELFGRDYC FSVIPNTNGD ICGHYPRHIV FLEYESSEKE KDTFESTVQV SKLQDLIHRS KMARCRGRFV CPVILFKGKH ICRSATLAGW GELYGRSGYN YFFSGGADDA WADVEDVTEE DCALRSGDTH LFDKVRGYDI KLLRYLSVKY ICDLMVENKK VKFGMNVTSS EKVDKAQRYA DFTLLSIPYP GCEFFKEYKD RDYMAEGLIF NWKQDYVDAP; Positive Samples: BT-474, Jurkat, Mouse liver, Mouse spleen, Mouse testis, Rat brain; Cellular Location: Cytoplasm

Target Information

This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hJumpy; jumpy; mJumpy; Myotubularin-related protein 14; NS5ATP4ABP1

Gene Aliases: 1110061O04Rik; AW553738; C3orf29; C76151; MTMR14; RGD1304842

UniProt ID: (Human) Q8NCE2, (Mouse) Q8VEL2

Entrez Gene ID: (Human) 64419, (Mouse) 97287, (Rat) 312634

Molecular Function: hydrolase phosphatase metabolite interconversion enzyme

Function(s)
phosphatidylinositol biosynthetic process macroautophagy peptidyl-tyrosine dephosphorylation dephosphorylation
Process(es)
phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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