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MYBPC3 Polyclonal Antibody
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Product Details
BS-9868R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human MYBPC3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac C-protein; cardiac MyBP-C; DKFZp779E1762; myosin binding protein C, cardiac; sarcomeric protein; unnamed protein product
Gene Aliases: CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C
UniProt ID: (Human) Q14896, (Rat) P56741
Entrez Gene ID: (Human) 4607, (Rat) 295929, (Mouse) 17868
heart morphogenesis
regulation of striated muscle contraction
regulation of muscle filament sliding
sarcomere organization
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
regulation of cardiac muscle cell contraction
regulation of heart rate
regulation of heart contraction
myosin filament assembly
muscle contraction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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