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MYBPC3 Antibody (PA5-88489) in IHC (P)
Immunohistochemistry analysis of MYBPC3 in paraffin-embedded mouse heart. Samples were incubated with MYBPC3 Polyclonal antibody (Product # PA5-88489) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-88489
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human MYBPC3 (NP_0002472)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804948
Product Specific Information
Immunogen sequence: SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQAP PSEYERIAFQ YGVTDLRGML KRLKGMRRDE KKSTAFQKKL EPAYQVSKGH KIRLTVELAD HDAEVKWLKN G; Positive Samples: Rat heart
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-protein, cardiac muscle isoform; cardiac C-protein; Cardiac MyBP-C; DKFZp779E1762; Myosin-binding protein C, cardiac-type
Gene Aliases: Mybpc3
UniProt ID: (Rat) P56741
Entrez Gene ID: (Rat) 295929, (Mouse) 17868
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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