This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
Immunogen sequence: QVEEDKVNSL SKSKVKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESIMDLE NDKLQLEEKL KKKEFDINQQ NSKIEDEQVL ALQLQKKLKE NQARIEELEE ELEAERTARA KVEKLRSDLS RELEEISERL EEA
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Binds to an epitope located within the peptide sequence KLEQQVDDLEGSLEQ as determined by overlapping synthetic peptides.
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
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Protein Aliases: MyHC-alpha; myosin 6; Myosin heavy chain 6; Myosin heavy chain, cardiac muscle alpha isoform; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); Myosin-6
Gene Aliases: alpha-MHC; ASD3; CMD1EE; CMH14; MYH6; MYHC; MYHCA; SSS3
UniProt ID: (Human) P13533
Entrez Gene ID: (Human) 4624