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Product Details
PA5-85510
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MYT1.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.96 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792650
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (97%), Rat (97%), Bovine (92%).
Positive Control: U87-MG, SK-N-SH nuclear, IMR32 nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; Neural zinc finger factor 2; neural zinc finger transcription factor 2; NZF-2; PLPB1; proteolipid protein binding protein; Proteolipid protein-binding protein
Gene Aliases: C20orf36; KIAA0835; KIAA1050; MTF1; MYT1; MYTI; NZF2; Nzf2a; Nzf2b; Nztf2; PLPB1; ZC2H2C1; ZC2HC4A
UniProt ID: (Human) Q01538, (Mouse) Q8CFC2
Entrez Gene ID: (Human) 4661, (Mouse) 17932
DNA binding
transcription factor activity, sequence-specific DNA binding
zinc ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
metal ion binding
zinc finger transcription factor
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