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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human Myostatin (GDF8)|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with bovine, porcine and non-human primate based on sequence homology.
GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Myostatin knockdown and its effect on myogenic gene expression program in stably transfected goat myoblasts.
PA5-11936 was used in western blot to study the effects of shRNA-mediated knockdown of myostatin on goat myoblast expression of myogenic genes
|Patel AK,Tripathi AK,Patel UA,Shah RK,Joshi CG||In vitro cellular & developmental biology. Animal (50:587)||2014|
compact; GDF-8; growth differentiation factor 8; growth/differentiation factor 8
Cmpt; GDF8; MSLHP; MSTN